Herpes Zoster (HZ): 

HZ is a painful rash that results from reactivation of the latent varicella-zoster virus (VZV). Primary infection with VZV causes chickenpox.1,2

Approximately 99.5% of adults in the US born before 1980 have been infected with VZV and are at risk of developing HZ. An estimated 1 million people develop HZ annually in the US. The risk of HZ increases with age.1

Risk Factors for Development of HZ1,3-5

Older Adults
Immunocompromised / Immunosuppressed
Sex
Medical History

Learn more about HZ in adults below​

Older Adults

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Pathogenesis and Epidemiology of Herpes Zoster

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  • • 6:14

Herpes Zoster: Impact and Burden of Disease

  • Video
  • • 3:09

Overview and Impact of Herpes Zoster

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Herpes Zoster: Clinical Presentation and Complications

  • Interactive Media

Herpes Zoster: Slide Presentation

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Immunocompromised / Immunosuppressed

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The risks of HZ in people with rheumatic disease

Dr Jeffrey Curtis

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  • • 9:10

Burden of HZ infographic (RA and PsA)

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Burden of HZ infographic (SLE)

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Herpes Zoster and Hematologic Malignancies

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Herpes Zoster and cancers common in Women

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Sex

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Herpes Zoster and cancers common in Women

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Medical History

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Burden of HZ in patients with asthma

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Burden of HZ in Patients COPD Infographic

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Patient Materials

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Overview and Impact of Herpes Zoster for Patients EN

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Overview and Impact of Herpes Zoster for Patients SP

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Abbreviations

EN English; HZ Herpes Zoster; IC Immunocompromised; IS Immunosuppressed; SP Spanish;  VZV Varicella Zoster Virus; US United States of America 

References

  1. Centers for Disease Control and Prevention. Clinical overview of shingles (herpes zoster). Available at: https://www.cdc.gov/shingles/hcp/clinical-overview/Open link icon. Last accessed: October 2024.​
  2. Leung J, et al. J Infect Dis 2022;226(Supp 4):S470–7
  3. Harpaz R, et al. MMWR Recomm Rep 2008;57(No. RR-5).
  4. Centers for Disease Control and Prevention. Epidemiology and prevention of vaccine-preventable diseases. 14th ed. 2021 Chapter 23: Zoster. Accessed October 2024. https://www.cdc.gov/pinkbook/hcp/table-of-contents/chapter-23-zoster.html Open link icon
  5. Marra F, et al. Open: Clinical Forum Infect Dis. 2020;7(1):ofaa005. doi: 10.1093/ofid/ofaa005.