Invasive Meningococcal Disease (IMD):

IMD is an uncommon but fast-onset and potentially life-threatening illness, with similar clinical presentation regardless of the causal serogroup.1

One IMD: One disease regardless of serogroup

IMD is an uncommon but unpredictable disease caused by Neisseria meningitidis that can lead to death or have severe and long-term consequences for survivors and their caregivers, even when diagnosed early and appropriate treatment is administered.1,2

IMD is rare, but peaks in incidence in infants, adolescents, and older adults.3

Clinical presentation of IMD, disease course, and consequences are similar, regardless of the causal serogroup. Almost all IMD is caused by serogroups A, B, C, W and Y.  In the US, serogroup B is the leading cause in adolescents and accounts for roughly half of all IMD cases in that age group. 1,4–7

There are vaccines available to help protect against the 5 disease-causing IMD serogroups: A, B, C, W, and Y.8

one-imd

Unmet needs in Invasive Meningococcal Disease

Disease overview

20%

Of individuals with IMD can have severe long-term outcomes

One in ten IMD cases may result in death, and up to 20% of individuals with IMD can experience serious long-term consequences.1,2

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Meningococcal vaccines for 5 disease-causing serogroups

Up to 87%

Of adolescents remain unvaccinated against 1 or more of these 5 serogroups.4,9

Awareness gaps hinder full vaccination coverage, leaving adolescents vulnerable.4 HCP recommendations greatly influence vaccination decisions.4

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Helping to protect adolescents and young adults against IMD

54%

Of young adults agreed that vaccination was the best way to help protect against IMD.10

A 2022 online survey of 606 US-based young adults and parents of older adolescents, showed a high interest in learning about IMD.10,11

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Learn more about Invasive Meningococcal Disease​

Disease overview

Did you know? Many survivors of IMD described transitioning from healthy or normal lives to becoming medically fragile and losing independence. Their caregivers experienced distress and impacts on their careers.12 Healthcare providers play an important role in sharing information to help prevent this potentially life-threatening disease. Talk to all of your adolescent and young adult patients about getting vaccinated against IMD.4,5,9

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Meningococcal Epidemiology and Disease Overview

  • Presentation

Neisseria Menigitidis disease epidemiology in the US

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The pink book: Epidemiology and Prevention of meningococcal disease

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Invasive Meningococcal Disease

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  • • 6:09

Meningococcal vaccines against 5 serogroups

Did you know? Different types of vaccines are available to help protect against 5 disease-causing serogroups.4,13

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Addressing disparities in MenACWY and MenB Vaccination Coverage

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CDC Meningococcal Information

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References

  1. CDC. Manual for the Surveillance of Vaccine-Preventable Diseases. Chapter 8: Meningococcal Disease. Rubis A, Schilie S. Last reviewed October 30, 2024. Accessed November 06, 2024. LinkOpen link icon
  2. Thompson MJ, et al. Lancet. 2006;367(9508):397–403. LinkOpen link icon
  3. CDC. Meningococcal Disease Surveillance and Trends. Last reviewed November 12, 2024. Accessed November 06, 2024. LinkOpen link icon
  4. Herrera-Restrepo O, et al. J Nurse Pract. 2024;20:1104793. LinkOpen link icon
  5. Herrera-Restrepo O, et al. J Adolesc Health. 2023;74(6):1131–1138. LinkOpen link icon
  6. CDC. Enhanced Meningococcal Disease Surveillance Report, 2022. Accessed October 11, 2024. LinkOpen link icon
  7. Rubis A. ACIP presentation, June 28, 2024. Accessed December 18, 2024. LinkOpen link icon
  8. CDC. Meningococcal Vaccine Recommendations. Last reviewed October 24, 2024. Accessed November 06, 2024. LinkOpen link icon
  9. Pingali C, et al. MMWR Morb Mortal Wkly Rep. 2023;72(34):912–919. LinkOpen link icon
  10. Herrera_Restrepo O, et al. Curr Med Res Opin. 2024;40:125–140. LinkOpen link icon
  11. Herrera-Restrepo O, et al. Curr Med Res Opin. 2024;40:1071–1074. LinkOpen link icon
  12. Herrera-Restrepo O, et al. Infect Dis Ther. 2024; Dec;13(12):2563–2579. LinkOpen link icon
  13. CDC. Recommended Child and Adolescent Immunization Schedule for ages 18 years or younger. Accessed October 11, 2024. LinkOpen link icon