• Uncomplicated Urinary Tract Infection (uUTI):

    UTIs are one of the most common infection-related diagnoses in US office-based provider practices1

    Up to 60% of women have at least one symptomatic UTI during their lifetime2–4

  • FACES OF UTI

    Faces of UTI are AI-infused clinical profiles that bring to life the results of an observational cluster analysis study on women who experience treatment failure after an uUTI. 

    Interact with Sarah, Jasmine, and Dorotha to learn more about how treatment failure impacts their daily life – in their own words!

  • UUTI introducing
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    Watch the Master Class series
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    uUTIs are common, burdensome, and rather complex. That’s why we developed the UTI Master Class, an educational video series led by experts and designed to empower primary care clinicians with high-impact, actionable insights relevant to daily practice

Did you know?

>1 in 8

women with
uUTI experience treatment failure5

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Defining Treatment Failure in uUTIs

Although relapse and recurrence are defined in clinical practice guidelines, treatment failure is not formally defined6–8

In two retrospective cohort studies involving approximately 610,000 women diagnosed with uUTIs in outpatient settings and prescribed empiric antibiotic therapy, treatment failure was defined by the occurrence of any of the following within 28 days of index date5,9:

uuti-antibiotic

A new or second oral antibiotic prescription for uUTI

uuti-antibiotic

Diagnosis of a UTI in an acute care setting

uuti-antibiotic

Administration of an IV antibiotic

Certain patient characteristics can increase risk of treatment failure9:

older-adult

Older age

History UTI

History of recurrent UTI

Oral antibiotics

# prescriptions for oral antibiotics in the prior year

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References

  1. Advani SD, et al. Antimicrob Steward Healthc Epidemiol. 2025;5(1):e143.
  2. Medina M., Castilo-Pino E. Ther Adv Urol. 2019 May 2:11:1756287219832172
  3. Lee HS, Le J. Urinary Tract Infections. 2018. https://www.accp.com/docs/bookstore/psap/p2018b1_sample.pdf
  4. Foxman B, Brown P. Infect Dis Clin N Am. 2003;17(2):227–241
  5. Franklin M, et al. Poster presented at: ISPOR 2023; May 7–10, 2023. Presentation EE548
  6. Nicolle LE, et al. Clin Infect Dis. 2005;40(5):643-654
  7. Anger J, et al. J Urol. 2019;202(2):282-2893
  8. Brubaker L, et al. Female Pelvic Med Reconstr Surg. 2018;24(5):321-335.
  9. Fromer DL, et al. J Gen Intern Med. 2024 Dec 16. doi: 10.1007/s11606-024-09265-w.