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>1 in 8

women with uUTI experience failure5

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Defining Treatment Failure in uUTIs

Although relapse and recurrence are defined in clinical practice guidelines, treatment failure is not formally defined6–8

In two retrospective cohort studies involving approximately 610,000 women diagnosed with uUTIs in outpatient settings and prescribed empiric antibiotic therapy, treatment failure was defined by the occurrence of any of the following within 28 days of index date5,9:

NA

A new or second oral antibiotic prescription for uUTI

NA

Diagnosis of a UTI in an acute care setting

NA

Administration of an IV antibiotic

Certain patient characteristics can increase risk of treatment failure9:

Results


Respiratory Syncytial Virus (RSV)

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    References

    1. Advani SD, et al. Antimicrob Steward Healthc Epidemiol. 2025;5(1):e143.
    2. Medina M., Castilo-Pino E. Ther Adv Urol. 2019 May 2:11:1756287219832172
    3. Lee HS, Le J. Urinary Tract Infections. 2018. https://www.accp.com/docs/bookstore/psap/p2018b1_sample.pdf
    4. Foxman B, Brown P. Infect Dis Clin N Am. 2003;17(2):227–241
    5. Franklin M, et al. Poster presented at: ISPOR 2023; May 7–10, 2023. Presentation EE548
    6. Nicolle LE, et al. Clin Infect Dis. 2005;40(5):643-654
    7. Anger J, et al. J Urol. 2019;202(2):282-2893
    8. Brubaker L, et al. Female Pelvic Med Reconstr Surg. 2018;24(5):321-335.
    9. Fromer DL, et al. J Gen Intern Med. 2024 Dec 16. doi: 10.1007/s11606-024-09265-w.