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Pipeline
At GSK, our pipeline is focused on unlocking the science of the immune system, human genetics, and advanced technologies to develop vaccines and specialty medicines.
Our products in development progress through three stages: phase I, phase II, and phase III/registrational. Each of these phases allows us to assess the safety and efficacy of our investigational products to eventually provide data to support applications for regulatory approval.
DISEASE STATES
mRNA COVID-19 2nd Gen vaccine candidate GSK4396687*
Safety and immunogenicity against SARS-CoV-2 in seropositive adults 18 years of age and older
mRNA COVID-19 2nd Gen vaccine candidate GSK4396687*
Safety and immune response in healthy adults
Cytomegalovirus (CMV) vaccine candidate GSK3993129*
Safety, reactogenicity, and immunogenicity in healthy adults 18 to 50 years of age
Gonorrhea Vaccine Candidate (GSK4348413)
Safety and efficacy in adults 18 to 50 years of age
Chronic hepatitis B targeted immunotherapy candidate GSK3528869*
Safety, immunogenicity, and efficacy study in adults 18-65 years of age with chronic hepatitis B on nucleo(s)tide treatment
Chronic hepatitis B targeted immunotherapy candidate GSK3528869*
Safety, immunogenicity, and efficacy in adults 18-65 years of age with chronic hepatitis B (CHB) following sequential treatment with an anti-sense oligonucleotide against CHB and CHB-targeted immunotherapy in patients receiving nucleos(t)ide analog therapy
iNTS (Invasive non-typhoidal salmonella prophylaxis) vaccine candidate GSK4077164*
Safety and immune response in adults 18-50 years of age
Klebsiella pneumoniae Tetravalent Bioconjugate Vaccine Candidate GSK4429016*
Multi-step study to assess safety and immunogenicity in healthy adults 18 to 40 and 55 to 70 years of age
MenABCWY 2nd Generation Vaccine Candidate GSK4023393*
Safety, effectiveness, and immunogenicity in healthy adolescents and adults 10 to 50 years of age
MenABCWY 2nd Generation Vaccine Candidate GSK4023393*
Safety, tolerability, and immune response in healthy infants 2 months of age at enrollment
Meningococcal Group B Vaccine GSK3536829*
Safety and immunogenicity of Bexsero when administered concomitantly with MenACWY conjugate vaccine (Menveo) to healthy infants (V72_56)
Safety and immunogenicity of 13-valent pneumococcal vaccine and Bexsero when administered together with routine infant vaccines in healthy infants (V72_57)
Randomized, observer-blind, multicenter study to assess the safety and immunogenicity of GSK's meningococcal group B vaccine when administered concomitantly with GSK's meningococcal MenACWY conjugate vaccine to healthy subjects of 16-18 years of age
MenABCWY 1st Generation Vaccine Candidate GSK3536819*
Randomized, observer-blind study in adolescents and young adults assessing the effectiveness of 2 doses or 3 doses of Bexsero and of 2 doses of GSK's investigational MenABCWY vaccine against a diverse panel of 110 invasive MenB strains.
Randomized, controlled, observer-blind study to evaluate safety and immunogenicity of GSK's meningococcal ABCWY vaccine when administered in healthy adolescents and adults, previously primed with meningococcal ACWY vaccine.
mRNA Influenza vaccine candidate GSK4382276*
Safety and immunogenicity in healthy adults 18-55 and 65 years and older
Safety, reactogenicity, and immunogenicity in healthy adults 18-45 years and 60-80 years of age
mRNA Influenza vaccine candidate GSK4382276*
Reactogenicity, safety, and immunogenicity in healthy adults aged 18-50 years (Phase 1) and 18-85 years of age (Phase 2)
S. pneumoniae vaccine candidate GSK5101956*
Safety, tolerability and immunogenicity in a dose-escalation study in toddlers 12 to 15 months of age
S. pneumoniae vaccine candidate GSK5101956*
Safety and tolerability in adults 18-64 years of age (Stage 1) and adults 65-85 years of age (Stage 2)
S. pneumoniae vaccine candidate GSK5101955*
Safety and immunogenicity in healthy infants 2 months of age
Salmonella Typhoid/Paratyphoid A Vaccine Candidate GSK3536867*
Safety in adults 18 to 50 years of age
Shigella vaccine candidate GSK3536852*
Assess efficacy, safety, and immunogenicity in healthy adults 18 to 50 years of age
Therapeutic herpes simplex virus (HSV) vaccine candidate GSK3943104*
Safety and immunogenicity in healthy adults 18-40 years of age (Step 1) and 18-60 years of age with recurrent Herpes Simplex Virus-2 (Step2)
Varicella New Strain vaccine candidate GSK4178116*
Immune response and safety in healthy children 12 to 15 months of age
Respiratory Syncytial Virus Vaccine, Adjuvanted
Immunogenicity and safety in adults 18 years and older with lung or kidney transplant compared to healthy adults
Respiratory Syncytial Virus Vaccine, Adjuvanted
Efficacy, safety, and immune response in preventing LRTD in adults 60 years and older
Immunogenicity in adults 18-49 years old at increased risk for RSV-LRTD compared to adults 60 years and older
Measles, Mumps, Rubella, Varicella New Strain Vaccine Candidate GSK4406371
Immunogenicity and safety in children 4 to 6 years of age
Malaria (Plasmodium falciparum, Next Generation)
Safety, efficacy and immunogenicity in children aged 5 to 17 months
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Disclaimer
This document contains information for healthcare providers and is intended solely for educational purposes. This display includes ongoing clinical trials for both approved and investigational compounds.
Some agents are approved in select indications. Inclusion in this display does not imply regulatory approval for these compounds or all indications. Information about all trials can be found at www.clinicaltrials.gov.
Footnotes
*In-license or other alliance relationship with third party.
